In 1688, a single Dutch settler arrived at the Cape of Good Hope and married an orphan from Rotterdam who had been sent there to find a husband; three centuries later, an estimated 8,000 of their descendants carry the gene that can turn ordinary anaesthetics fatal

Home Breaking News In 1688, a single Dutch settler arrived at the Cape of Good Hope and married an orphan from Rotterdam who had been sent there to find a husband; three centuries later, an estimated 8,000 of their descendants carry the gene that can turn ordinary anaesthetics fatal
A hidden genetic vulnerability, stemming from a single colonial marriage in the late 1600s, can turn routine medical procedures into life-threatening crises for some South Africans. This inherited trait, affecting heme production, can cause severe reactions to common sedatives. Medical teams now screen for this specific marker, altering anesthetic guidelines to protect a population unknowingly carrying this historical legacy.